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A Nuclear Magnetic Resonance Investigation of the Energetics of Basepair Opening Pathways in DNA

The opening of basepairs plays a key role in DNA replication and transcription, and in the action of DNA repair and modification enzymes. In this article, we have used proton exchange to define the energetics of the pathways for basepair opening in two DNA 17-mer duplexes. The rates of exchange of i...

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Библиографические подробности
Главные авторы: Coman, Daniel, Russu, Irina M.
Формат: Artigo
Язык:Inglês
Опубликовано: Biophysical Society 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366824/
https://ncbi.nlm.nih.gov/pubmed/16126830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065763
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