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A Nuclear Magnetic Resonance Investigation of the Energetics of Basepair Opening Pathways in DNA

The opening of basepairs plays a key role in DNA replication and transcription, and in the action of DNA repair and modification enzymes. In this article, we have used proton exchange to define the energetics of the pathways for basepair opening in two DNA 17-mer duplexes. The rates of exchange of i...

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Bibliografiske detaljer
Main Authors: Coman, Daniel, Russu, Irina M.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366824/
https://ncbi.nlm.nih.gov/pubmed/16126830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065763
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