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Sequence-Dependence of the Energetics of Opening of AT Basepairs in DNA

Proton exchange and nuclear magnetic resonance spectroscopy are being used to characterize the energetics of opening of AT/TA basepairs in the DNA dodecamer 5′-d(GCTATAAAAGGG)-3′/5′-d(CCCTTTTATAGC)-3′. The dodecamer contains the TATA box of the adenovirus major late promoter. The equilibrium constan...

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Autori principali: Chen, Congju, Russu, Irina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304673/
https://ncbi.nlm.nih.gov/pubmed/15454449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.045179
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