Sequence-Dependent Basepair Opening in DNA Double Helix

Preservation of genetic information in DNA relies on shielding the nucleobases from damage within the double helix. Thermal fluctuations lead to infrequent events of the Watson-Crick basepair opening, or DNA “breathing”, thus making normally buried groups available for modification and interaction w...

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Bibliografske podrobnosti
Main Authors: Krueger, Andrew, Protozanova, Ekaterina, Frank-Kamenetskii, Maxim D.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Biophysical Theory and Modeling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1432109/
https://ncbi.nlm.nih.gov/pubmed/16500982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.078774
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