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Base-stacking and base-pairing contributions into thermal stability of the DNA double helix

Two factors are mainly responsible for the stability of the DNA double helix: base pairing between complementary strands and stacking between adjacent bases. By studying DNA molecules with solitary nicks and gaps we measure temperature and salt dependence of the stacking free energy of the DNA doubl...

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Detalhes bibliográficos
Main Authors: Yakovchuk, Peter, Protozanova, Ekaterina, Frank-Kamenetskii, Maxim D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360284/
https://ncbi.nlm.nih.gov/pubmed/16449200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj454
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