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Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids

If adenines and thymines in two mutually complementary mixed-base peptide nucleic acid (PNA) oligomers are substituted with diaminopurines and thiouracils, respectively, so-called pseudocomplementary PNAs (pcPNAs) are created. Pairs of pcPNAs have recently demonstrated an ability to highly selective...

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Detalhes bibliográficos
Main Authors: Demidov, Vadim V., Protozanova, Ekaterina, Izvolsky, Konstantin I., Price, Christopher, Nielsen, Peter E., Frank-Kamenetskii, Maxim D.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122883/
https://ncbi.nlm.nih.gov/pubmed/11972051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.092127999
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