Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA.

Strand displacement binding kinetics of cationic pseudoisocytosine-containing linked homopyrimidine peptide nucleic acids (bis-PNAs) to fully matched and singly mismatched decapurine targets in double-stranded DNA (dsDNA) are reported. PNA-dsDNA complex formation was monitored by gel mobility shift...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Kuhn, H, Demidov, V V, Frank-Kamenetskii, M D, Nielsen, P E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147306/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9421519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.2.582
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