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Kinetic sequence discrimination of cationic bis-PNAs upon targeting of double-stranded DNA.

Strand displacement binding kinetics of cationic pseudoisocytosine-containing linked homopyrimidine peptide nucleic acids (bis-PNAs) to fully matched and singly mismatched decapurine targets in double-stranded DNA (dsDNA) are reported. PNA-dsDNA complex formation was monitored by gel mobility shift...

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Bibliografische gegevens
Hoofdauteurs: Kuhn, H, Demidov, V V, Frank-Kamenetskii, M D, Nielsen, P E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147306/
https://ncbi.nlm.nih.gov/pubmed/9421519
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