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Sequence dependency of canonical base pair opening in the DNA double helix

The flipping-out of a DNA base from the double helical structure is a key step of many cellular processes, such as DNA replication, modification and repair. Base pair opening is the first step of base flipping and the exact mechanism is still not well understood. We investigate sequence effects on b...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Lindahl, Viveca, Villa, Alessandra, Hess, Berk
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393899/
https://ncbi.nlm.nih.gov/pubmed/28369121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005463
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