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Triple helical DNA in a duplex context and base pair opening

It is fundamental to explore in atomic detail the behavior of DNA triple helices as a means to understand the role they might play in vivo and to better engineer their use in genetic technologies, such as antigene therapy. To this aim we have performed atomistic simulations of a purine-rich antipara...

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Detalhes bibliográficos
Main Authors: Esguerra, Mauricio, Nilsson, Lennart, Villa, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191418/
https://ncbi.nlm.nih.gov/pubmed/25228466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku848
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