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Triple helical DNA in a duplex context and base pair opening

It is fundamental to explore in atomic detail the behavior of DNA triple helices as a means to understand the role they might play in vivo and to better engineer their use in genetic technologies, such as antigene therapy. To this aim we have performed atomistic simulations of a purine-rich antipara...

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Hlavní autoři: Esguerra, Mauricio, Nilsson, Lennart, Villa, Alessandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191418/
https://ncbi.nlm.nih.gov/pubmed/25228466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku848
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