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Free energy landscape and transition pathways from Watson–Crick to Hoogsteen base pairing in free duplex DNA

Houghton (HG) base pairing plays a central role in the DNA binding of proteins and small ligands. Probing detailed transition mechanism from Watson–Crick (WC) to HG base pair (bp) formation in duplex DNAs is of fundamental importance in terms of revealing intrinsic functions of double helical DNAs b...

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Publicat a:Nucleic Acids Res
Autors principals: Yang, Changwon, Kim, Eunae, Pak, Youngshang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652778/
https://ncbi.nlm.nih.gov/pubmed/26250116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv796
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