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Lac repressor hinge flexibility and DNA looping: single molecule kinetics by tethered particle motion

The tethered particle motion (TPM) allows the direct detection of activity of a variety of biomolecules at the single molecule level. First pioneered for RNA polymerase, it has recently been applied also to other enzymes. In this work we employ TPM for a systematic investigation of the kinetics of D...

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Autors principals: Vanzi, Francesco, Broggio, Chiara, Sacconi, Leonardo, Pavone, Francesco Saverio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1524907/
https://ncbi.nlm.nih.gov/pubmed/16835309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl393
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