Glatiramer Acetate and Nanny Proteins Restrict Access of the Multiple Sclerosis Autoantigen Myelin Basic Protein to the 26S Proteasome

We recently showed that myelin basic protein (MBP) is hydrolyzed by 26S proteasome without ubiquitination. The previously suggested concept of charge-mediated interaction between MBP and the proteasome led us to attempt to compensate or mimic its positive charge to inhibit proteasomal degradation. W...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kuzina, Ekaterina, Kudriaeva, Anna, Smirnov, Ivan, Dubina, Michael V., Gabibov, Alexander, Belogurov, Alexey
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172982/
https://ncbi.nlm.nih.gov/pubmed/25276831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/926394
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky