Interplay of dFOXO and Two ETS-Family Transcription Factors Determines Lifespan in Drosophila melanogaster

Forkhead box O (FoxO) transcription factors (TFs) are key drivers of complex transcriptional programmes that determine animal lifespan. FoxOs regulate a number of other TFs, but how these TFs in turn might mediate the anti-ageing programmes orchestrated by FoxOs in vivo is unclear. Here, we identify...

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Bibliografiske detaljer
Main Authors: Alic, Nazif, Giannakou, Maria E., Papatheodorou, Irene, Hoddinott, Matthew P., Andrews, T. Daniel, Bolukbasi, Ekin, Partridge, Linda
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169242/
https://ncbi.nlm.nih.gov/pubmed/25232726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004619
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