dFOXO-independent effects of reduced insulin-like signaling in Drosophila

The insulin/insulin-like growth factor-like signaling (IIS) pathway in metazoans has evolutionarily conserved roles in growth control, metabolic homeostasis, stress responses, reproduction, and lifespan. Genetic manipulations that reduce IIS in the nematode worm Caenorhabditis elegans, the fruit fly...

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Autores principales: Slack, Cathy, Giannakou, Maria E, Foley, Andrea, Goss, Martin, Partridge, Linda
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2011
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193374/
https://ncbi.nlm.nih.gov/pubmed/21443682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00707.x
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