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Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice
Down-regulation of insulin/insulin-like growth factor signaling (IIS) can increase lifespan in C. elegans, Drosophila and mice. In C. elegans, reduced IIS results in down-regulation of translation, which itself can extend lifespan. However, the effect of reduced IIS on translation has yet to be dete...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959029/ https://ncbi.nlm.nih.gov/pubmed/27452396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30290 |
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