Cell-Nonautonomous Effects of dFOXO/DAF-16 in Aging

Drosophila melanogaster and Caenorhabditis elegans each carry a single representative of the Forkhead box O (FoxO) family of transcription factors, dFOXO and DAF-16, respectively. Both are required for lifespan extension by reduced insulin/Igf signaling, and their activation in key tissues can exten...

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Main Authors: Alic, Nazif, Tullet, Jennifer M., Niccoli, Teresa, Broughton, Susan, Hoddinott, Matthew P., Slack, Cathy, Gems, David, Partridge, Linda
格式: Artigo
語言:Inglês
出版: Cell Press 2014
主題:
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969275/
https://ncbi.nlm.nih.gov/pubmed/24508462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.01.015
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