Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

FoxO transcription factors, inhibited by insulin/insulin-like growth factor signalling (IIS), are crucial players in numerous organismal processes including lifespan. Using genomic tools, we uncover over 700 direct dFOXO targets in adult female Drosophila. dFOXO is directly required for transcriptio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Alic, Nazif, Andrews, T Daniel, Giannakou, Maria E, Papatheodorou, Irene, Slack, Cathy, Hoddinott, Matthew P, Cochemé, Helena M, Schuster, Eugene F, Thornton, Janet M, Partridge, Linda
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: European Molecular Biology Organization 2011
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159968/
https://ncbi.nlm.nih.gov/pubmed/21694719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2011.36
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