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Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor
Mammals possess multiple insulin-like growth factor (IGF) binding proteins (IGFBPs), and related proteins, that modulate the activity of insulin/IGF signalling (IIS), a conserved neuroendocrine signalling pathway that affects animal lifespan. Here, we examine if increased levels of an IGFBP-like pro...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Publishing Ltd
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042147/ https://ncbi.nlm.nih.gov/pubmed/21108726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2010.00653.x |
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