X-ray Structure of a NF-κB p50/RelB/DNA Complex Reveals Assembly of Multiple Dimers on Tandem κB Sites

We describe here the X-ray crystal structure of NF-κB p50/RelB heterodimer bound to a κB DNA. Although the global modes of subunit association and κB DNA recognition are similar to other NF-κB/DNA complexes, this complex reveals distinctive features not observed for non-RelB complexes. For example,...

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Hlavní autoři: Moorthy, Anu K., Huang, De-Bin, Wang, Vivien Ya-Fan, Vu, Don, Ghosh, Gourisankar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167888/
https://ncbi.nlm.nih.gov/pubmed/17869269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.08.039
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