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NF-κB p52:RelB heterodimer recognizes two classes of κB sites with two distinct modes
The X-ray structure of the nuclear factor-κB (NF-κB) p52:RelB:κB DNA complex reveals a new recognition feature not previously seen in other NF-κB:κB DNA complexes. Arg 125 of RelB is in contact with an additional DNA base pair. Surprisingly, the p52:RelB R125A mutant heterodimer shows defects both i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637311/ https://ncbi.nlm.nih.gov/pubmed/19098713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.227 |
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