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The 20S proteasome processes NF-κB1 p105 into p50 in a translation-independent manner

The NF-κB p50 is the N-terminal processed product of the precursor, p105. It has been suggested that p50 is generated not from full-length p105 but cotranslationally from incompletely synthesized molecules by the proteasome. We show that the 20S proteasome endoproteolytically cleaves the fully synth...

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Detalhes bibliográficos
Main Authors: Moorthy, Anu K, Savinova, Olga V, Ho, Jessica Q, Wang, Vivien Ya-Fan, Vu, Don, Ghosh, Gourisankar
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456938/
https://ncbi.nlm.nih.gov/pubmed/16619030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601081
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