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The Nfkb1 and Nfkb2 Proteins p105 and p100 Function as the Core of High-Molecular-Weight Heterogeneous Complexes

Nfkb1 and Nfkb2 proteins p105 and p100 serve both as NF-κB precursors and inhibitors of NF-κB dimers. In a biochemical characterization of endogenous cytoplasmic and purified recombinant proteins, we found that p105 and p100 assemble into high-molecular-weight complexes that contribute to the regula...

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Detalhes bibliográficos
Main Authors: Savinova, Olga V., Hoffmann, Alexander, Ghosh, Gourisankar
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167889/
https://ncbi.nlm.nih.gov/pubmed/19524538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.04.033
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