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Sex-dependent, zinc-induced dephosphorylation of phospholamban by tissue-nonspecific alkaline phosphatase in the cardiac sarcomere

We have previously reported that Zn(2+) infused into the coronary arteries of isolated rat hearts leads to the potent dephosphorylation of phospholamban (PLB) as well as a noticeable but less potent dephosphorylation of the ryanodine receptor 2. We hypothesized in the present study that a Zn(2+)-act...

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Hlavní autoři: Wang, Yuan, Bishop, Nicole M., Taatjes, Douglas J., Narisawa, Sonoko, Millán, José Luis, Palmer, Bradley M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166743/
https://ncbi.nlm.nih.gov/pubmed/25015959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00374.2014
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