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Identification and Characterization of Novel Tissue-Nonspecific Alkaline Phosphatase Inhibitors with Diverse Modes of Action

Tissue-nonspecific alkaline phosphatase (TNAP) plays a major role in maintaining a ratio of phosphate to inorganic pyrophosphate (P(i)/PP(i)) in biological fluids that is conducive to controlled skeletal mineralization while preventing inappropriate ectopic calcification. Medial calcification associ...

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Detalhes bibliográficos
Main Authors: Sergienko, Eduard, Su, Ying, Garcia, Xochella, Brown, Brock, Hurder, Andrew, Narisawa, Sonoko, Millán, José Luis
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403534/
https://ncbi.nlm.nih.gov/pubmed/19556612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057109338517
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