Interactions of Disulfide-deficient Selenocysteine Analogs of μ-Conotoxin BuIIIB with the Voltage-Gated Sodium Channel Na(V)1.3

Inhibitors of the neuronal voltage-gated sodium channel subtype Na(V)1.3 are of interest as pharmacological tools for the study of neuropathic pain associated with spinal cord injury and have potential therapeutic applications. The recently described μ-conotoxin BuIIIB from Conus bullatus (μ-BuIIIB)...

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Hlavní autoři: Green, Brad R., Zhang, Min-Min, Chhabra, Sandeep, Robinson, Samuel D., Wilson, Michael J., Redding, Addison, Olivera, Baldomero M., Yoshikami, Doju, Bulaj, Grzegorz, Norton, Raymond S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160447/
https://ncbi.nlm.nih.gov/pubmed/24814369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12835
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