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Enhanced dissolution and stability of Tanshinone IIA base by solid dispersion system with nano-hydroxyapatite

BACKGROUND: Tanshinone IIA (TSIIA) exhibits a variety of cardiovascular effects; however, it has low solubility in water. The preparation of poorly soluble drugs for oral delivery is one of the greatest challenges in the field of formulation research. Among the approaches available, solid dispersion...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jiang, Yan-rong, Zhang, Zhen-hai, Huang, Sai-yan, Lu, Yan, Ma, Tian-tian, Jia, Xiao-bin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Medknow Publications & Media Pvt Ltd 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159928/
https://ncbi.nlm.nih.gov/pubmed/25210322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.137375
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