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Enhanced dissolution and stability of Tanshinone IIA base by solid dispersion system with nano-hydroxyapatite
BACKGROUND: Tanshinone IIA (TSIIA) exhibits a variety of cardiovascular effects; however, it has low solubility in water. The preparation of poorly soluble drugs for oral delivery is one of the greatest challenges in the field of formulation research. Among the approaches available, solid dispersion...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159928/ https://ncbi.nlm.nih.gov/pubmed/25210322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.137375 |
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