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An attempt to stabilize tanshinone IIA solid dispersion by the use of ternary systems with nano-CaCO(3) and poloxamer 188

BACKGROUND: Tanshinone IIA (TSIIA) on solid dispersions (SDs) has thermodynamical instability of amorphous drug. Ternary solid dispersions (tSDs) can extend the stability of the amorphous form of drug. Poloxamer 188 was used as a SD carrier. Nano-CaCO(3) played an important role in adsorption of bio...

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Detalhes bibliográficos
Main Authors: Yan, Hong-mei, Zhang, Zhen-hai, Jiang, Yan-rong, Ding, Dong-mei, Sun, E., Jia, Xiao-bin
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078353/
https://ncbi.nlm.nih.gov/pubmed/24991109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.133286
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