Preparation, characterization, and in vivo evaluation of tanshinone IIA solid dispersions with silica nanoparticles

We prepared solid dispersions (SDs) of tanshinone IIA (TSIIA) with silica nanoparticles, which function as dispersing carriers, using a spray-drying method and evaluated their in vitro dissolution and in vivo performance. The extent of TSIIA dissolution in the silica nanoparticles/TSIIA system (weig...

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Bibliografiske detaljer
Main Authors: Jiang, Yan-rong, Zhang, Zhen-hai, Liu, Qi-yuan, Hu, Shao-ying, Chen, Xiao-yun, Jia, Xiao-bin
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2013
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699171/
https://ncbi.nlm.nih.gov/pubmed/23836971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S40374
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