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Enhanced dissolution and stability of Tanshinone IIA base by solid dispersion system with nano-hydroxyapatite

BACKGROUND: Tanshinone IIA (TSIIA) exhibits a variety of cardiovascular effects; however, it has low solubility in water. The preparation of poorly soluble drugs for oral delivery is one of the greatest challenges in the field of formulation research. Among the approaches available, solid dispersion...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Jiang, Yan-rong, Zhang, Zhen-hai, Huang, Sai-yan, Lu, Yan, Ma, Tian-tian, Jia, Xiao-bin
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Medknow Publications & Media Pvt Ltd 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159928/
https://ncbi.nlm.nih.gov/pubmed/25210322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.137375
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