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Role of TGFβ signaling in generation of CD39(+)CD73(+) myeloid cells in tumors
There is growing evidence that generation of adenosine from ATP, which is mediated by the CD39/CD73 enzyme pair, predetermines immunosuppressive and pro-angiogenic properties of myeloid cells. We have previously shown that the deletion of the TGFβ type II receptor gene (Tgfbr2) expression in myeloid...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157098/ https://ncbi.nlm.nih.gov/pubmed/25127858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400578 |
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