TGFβ Signaling in Myeloid Cells Regulates Mammary Carcinoma Cell Invasion through Fibroblast Interactions

Metastasis is the most devastating aspect of cancer, however we know very little about the mechanisms of local invasion, the earliest step of metastasis. During tumor growth CD11b(+)Gr1(+) cells, known also as MDSCs, have been shown to promote tumor progression by a wide spectrum of effects that sup...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shaw, Aubie K., Pickup, Michael W., Chytil, Anna, Aakre, Mary, Owens, Philip, Moses, Harold L., Novitskiy, Sergey V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309578/
https://ncbi.nlm.nih.gov/pubmed/25629162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117908
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