Myeloid cell-derived TGF-beta signaling regulates ECM deposition in mammary carcinoma via adenosine-dependent mechanisms

TGFβ plays a crucial role in the tumor microenvironment by regulating cell-cell and cell-stroma interactions. We previously demonstrated that TGFβ signaling on myeloid cells regulates expression of CD73, a key enzyme for production of adenosine, a pro-tumorigenic metabolite implicated in regulation...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Vasiukov, Georgii, Novitskaya, Tatiana, Zijlstra, Andries, Owens, Phillip, Ye, Fei, Zhao, Zhiguo, Moses, Harold L., Blackwell, Timothy, Feoktistov, Igor, Novitskiy, Sergey V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7299805/
https://ncbi.nlm.nih.gov/pubmed/32312837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3954
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