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CFTR Degradation: Cross-talk between the Ubiquitylation and SUMOylation Pathways

Defining the significant checkpoints in CFTR biogenesis should identify targets for therapeutic intervention with CFTR folding mutants like F508del. While the role of ubiquitylation and the ubiquitin proteasome system is well established in the degradation of this common CFTR mutant, the part played...

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Bibliografski detalji
Glavni autori: Ahner, Annette, Gong, Xaioyan, Frizzell, Raymond A.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156008/
https://ncbi.nlm.nih.gov/pubmed/23809253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12415
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