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Divergent signaling via SUMO modification: potential for CFTR modulation

The cystic fibrosis transmembrane conductance regulator (CFTR) is generally responsible for the cAMP/PKA regulated anion conductance at the apical membranes of secretory epithelial cells. Mutations in CFTR underlie cystic fibrosis (CF), in which the most common variant, F508del, causes protein misfo...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Ahner, Annette, Gong, Xiaoyan, Frizzell, Raymond A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838058/
https://ncbi.nlm.nih.gov/pubmed/26582473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00124.2015
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