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CFTR Degradation: Cross-talk between the Ubiquitylation and SUMOylation Pathways
Defining the significant checkpoints in CFTR biogenesis should identify targets for therapeutic intervention with CFTR folding mutants like F508del. While the role of ubiquitylation and the ubiquitin proteasome system is well established in the degradation of this common CFTR mutant, the part played...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156008/ https://ncbi.nlm.nih.gov/pubmed/23809253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12415 |
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