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CFTR Degradation: Cross-talk between the Ubiquitylation and SUMOylation Pathways

Defining the significant checkpoints in CFTR biogenesis should identify targets for therapeutic intervention with CFTR folding mutants like F508del. While the role of ubiquitylation and the ubiquitin proteasome system is well established in the degradation of this common CFTR mutant, the part played...

詳細記述

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書誌詳細
主要な著者: Ahner, Annette, Gong, Xaioyan, Frizzell, Raymond A.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156008/
https://ncbi.nlm.nih.gov/pubmed/23809253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12415
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