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TLR2 Signaling is Required for the Innate, but Not Adaptive Response to LVS clpB
Toll-like receptor 2 (TLR2) is the best-characterized pattern-recognition receptor for the highly pathogenic intracellular bacterium, Francisella tularensis. We previously identified a mutant in the live vaccine strain (LVS) of Francisella, LVS clpB, which is attenuated, but induces a protective imm...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155801/ https://ncbi.nlm.nih.gov/pubmed/25250027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00426 |
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