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Prion propagation can occur in a prokaryote and requires the ClpB chaperone
Prions are self-propagating protein aggregates that are characteristically transmissible. In mammals, the PrP protein can form a prion that causes the fatal transmissible spongiform encephalopathies. Prions have also been uncovered in fungi, where they act as heritable, protein-based genetic element...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150125/ https://ncbi.nlm.nih.gov/pubmed/25122461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02949 |
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