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Prion propagation can occur in a prokaryote and requires the ClpB chaperone

Prions are self-propagating protein aggregates that are characteristically transmissible. In mammals, the PrP protein can form a prion that causes the fatal transmissible spongiform encephalopathies. Prions have also been uncovered in fungi, where they act as heritable, protein-based genetic element...

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Bibliographic Details
Main Authors: Yuan, Andy H, Garrity, Sean J, Nako, Entela, Hochschild, Ann
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150125/
https://ncbi.nlm.nih.gov/pubmed/25122461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02949
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