Infection with Francisella tularensis LVS clpB Leads to an Altered yet Protective Immune Response

Bacterial attenuation is typically thought of as reduced bacterial growth in the presence of constant immune pressure. Infection with Francisella tularensis elicits innate and adaptive immune responses. Several in vivo screens have identified F. tularensis genes necessary for virulence. Many of thes...

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Main Authors: Barrigan, Lydia M., Tuladhar, Shraddha, Brunton, Jason C., Woolard, Matthew D., Chen, Ching-ju, Saini, Divey, Frothingham, Richard, Sempowski, Gregory D., Kawula, Thomas H., Frelinger, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2013
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676025/
https://ncbi.nlm.nih.gov/pubmed/23529616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00207-13
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