Infection with Francisella tularensis LVS clpB Leads to an Altered yet Protective Immune Response

Bacterial attenuation is typically thought of as reduced bacterial growth in the presence of constant immune pressure. Infection with Francisella tularensis elicits innate and adaptive immune responses. Several in vivo screens have identified F. tularensis genes necessary for virulence. Many of thes...

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Bibliographische Detailangaben
Hauptverfasser: Barrigan, Lydia M., Tuladhar, Shraddha, Brunton, Jason C., Woolard, Matthew D., Chen, Ching-ju, Saini, Divey, Frothingham, Richard, Sempowski, Gregory D., Kawula, Thomas H., Frelinger, Jeffrey A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Microbial Immunity and Vaccines
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676025/
https://ncbi.nlm.nih.gov/pubmed/23529616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00207-13
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