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ClpB mutants of Francisella tularensis subspecies holarctica and tularensis are defective for type VI secretion and intracellular replication

Francisella tularensis, a highly infectious, intracellular bacterium possesses an atypical type VI secretion system (T6SS), which is essential for the virulence of the bacterium. Recent data suggest that the HSP100 family member, ClpB, is involved in T6SS disassembly in the subspecies Francisella no...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Alam, Athar, Golovliov, Igor, Javed, Eram, Sjöstedt, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063899/
https://ncbi.nlm.nih.gov/pubmed/30054549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29745-4
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