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Dissociation between the critical role of ClpB of Francisella tularensis for the heat shock response and the DnaK interaction and its important role for efficient type VI secretion and bacterial virulence

Francisella tularensis, a highly infectious, intracellular bacterium possesses an atypical type VI secretion system (T6SS), which is essential for its virulence. The chaperone ClpB, a member of the Hsp100/Clp family, is involved in Francisella T6SS disassembly and type VI secretion (T6S) is impaired...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Alam, Athar, Golovliov, Igor, Javed, Eram, Kumar, Rajender, Ådén, Jörgen, Sjöstedt, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182274/
https://ncbi.nlm.nih.gov/pubmed/32275693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008466
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