Infection with Francisella tularensis LVS clpB Leads to an Altered yet Protective Immune Response

Bacterial attenuation is typically thought of as reduced bacterial growth in the presence of constant immune pressure. Infection with Francisella tularensis elicits innate and adaptive immune responses. Several in vivo screens have identified F. tularensis genes necessary for virulence. Many of thes...

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Hlavní autoři: Barrigan, Lydia M., Tuladhar, Shraddha, Brunton, Jason C., Woolard, Matthew D., Chen, Ching-ju, Saini, Divey, Frothingham, Richard, Sempowski, Gregory D., Kawula, Thomas H., Frelinger, Jeffrey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676025/
https://ncbi.nlm.nih.gov/pubmed/23529616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00207-13
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