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IFN-γ, but not IL-17A, is required for survival during secondary pulmonary Francisella tularensis Live Vaccine Stain infection

IL-17 and IFN-γ production by Th17 and Th1 cells, respectively, is critical for survival during primary respiratory infection with the pathogenic bacterium, Francisella tularensis Live Vaccine Strain (LVS). The importance, however, of these T cell subsets and their soluble mediators is not well unde...

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Detalhes bibliográficos
Main Authors: Roberts, Lydia M., Davies, John S., Sempowski, Gregory D., Frelinger, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075325/
https://ncbi.nlm.nih.gov/pubmed/24837506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.05.013
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