IL-10 Restrains IL-17 to Limit Lung Pathology Characteristics following Pulmonary Infection with Francisella tularensis Live Vaccine Strain

IL-10 production during intracellular bacterial infections is generally thought to be detrimental because of its role in suppressing protective T-helper cell 1 (Th1) responses. Francisella tularensis is a facultative intracellular bacterium that activates both Th1 and Th17 protective immune response...

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Autores principales: Slight, Samantha R., Monin, Leticia, Gopal, Radha, Avery, Lyndsay, Davis, Marci, Cleveland, Hillary, Oury, Tim D., Rangel-Moreno, Javier, Khader, Shabaana A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2013
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814571/
https://ncbi.nlm.nih.gov/pubmed/24007881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.07.008
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