Immune requirements for protective Th17 recall responses to Mycobacterium tuberculosis challenge

Tuberculosis (TB) vaccine development has focused largely on targeting T helper type 1 (Th1) cells. However, despite inducing Th1 cells, the recombinant TB vaccine MVA85A failed to enhance protection against TB disease in humans. In recent years, Th17 cells have emerged as key players in vaccine-ind...

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Bibliographic Details
Published in:Mucosal Immunol
Main Authors: Monin, Leticia, Griffiths, Kristin, Slight, Samantha, Lin, Yin-yao, Rangel-Moreno, Javier, Khader, Shabaana A.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517980/
https://ncbi.nlm.nih.gov/pubmed/25627812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.136
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