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Francisella tularensis LVS-induced Interleukin-12 p40 cytokine production mediates Dendritic cell migration through IL-12 Receptor β1

Three cytokines use the IL-12p40 cytokine subunit namely: IL-12p70 (IL-12-comprised of IL-12p40 and IL-12p35), IL-23 (comprised of the IL-12p40 and IL-23p19 subunits) and homodimeric IL-12p40 (IL-12(p40)(2)). Following activation, immature dendritic cells (DCs) upregulate the chemokine receptor Chem...

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Detalhes bibliográficos
Main Authors: Slight, Samantha R., Lin, Yinyao, Messmer, Michelle, Khader, Shabaana A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148298/
https://ncbi.nlm.nih.gov/pubmed/21669537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2011.05.017
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