Real-time detection of DNA hybridization and melting on oligonucleotide arrays by using optical wave guides.
The challenge of the Human Genome Project is to increase the rate of DNA sequence acquisition by two orders of magnitude to complete sequencing of the human genome by the year 2000. The present work describes a rapid detection method using a two-dimensional optical wave guide that allows measurement...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1995
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7603999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6379 |
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