Real-time detection of DNA hybridization and melting on oligonucleotide arrays by using optical wave guides.

The challenge of the Human Genome Project is to increase the rate of DNA sequence acquisition by two orders of magnitude to complete sequencing of the human genome by the year 2000. The present work describes a rapid detection method using a two-dimensional optical wave guide that allows measurement...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Stimpson, D I, Hoijer, J V, Hsieh, W T, Jou, C, Gordon, J, Theriault, T, Gamble, R, Baldeschwieler, J D
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41521/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7603999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6379
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