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DNA analysis and diagnostics on oligonucleotide microchips.

We present a further development in the technology of sequencing by hybridization to oligonucleotide microchips (SHOM) and its application to diagnostics for genetic diseases. A robot has been constructed to manufacture sequencing "microchips." The microchip is an array of oligonucleotides immobiliz...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Yershov, G, Barsky, V, Belgovskiy, A, Kirillov, E, Kreindlin, E, Ivanov, I, Parinov, S, Guschin, D, Drobishev, A, Dubiley, S, Mirzabekov, A
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4913
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